Multiple forms of somatostatin-like immunoreactivity in canine pancreas

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[Immunohistochemical demonstration of somatostatin-28 like immunoreactivity in the fetal and adult human gut and pancreas].

In order to examine whether somatostatin-28 originally isolated from porcine and ovine tissues was present in the human gut and pancreas or not, immunohistochemical methods using specific antisera against somatostatin-28 and somatostatin-14 antisera were carried out in the fetal and adult human gut and pancreas. The specific antisera against somatostatin-28 were prepared from somatostatin-28 an...

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CXCL14-Like Immunoreactivity Exists in Somatostatin-Containing Cells of Mouse Pancreas

Immunohistochemical techniques were employed to investigate the distribution of the chemokine CXCL14, in the mouse pancreas. CXCL14-immunoreactive cells were detected in the peripheral region of the pancreatic islets and were immunoreactive for somatostatin, but not for glucagon, insulin, and pancreatic polypeptide. Immunoelectron microscopy indicated that the CXCL14-like peptide and somatostat...

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Contribution of the pancreas to circulating somatostatin-like immunoreactivity in the normal dog.

These studies were performed to assess the contribution of the pancreas to the somatostatin-like immunoreactivity (SLI) circulating in arterial and portal venous plasma. Basal SLI concentrations in arterial, pancreatic venous, and portal venous plasma were 95 +/- 9, 277 +/- 32, and 130 +/- 12 pg/ml, (means +/- SEM), respectively. Measurement of pancreatic and portal venous blood flow (5 +/- 1 v...

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Bacillus subtilis contains multiple forms of somatostatin-like material.

Extracts of B. subtilis contain somatostatin-like immunoactivity (1-20 pg per g wet weight cells). Two major forms were detected, one with reactivity in both N- and C-terminal immunoassays similar to somatostatin-28 and a second form reactive only in the C-terminal specific immunoassay similar to somatostatin-14. Both forms were active in a bioassay and the bioactivity was neutralized in the pr...

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Release of somatostatin-like immunoreactivity from the perfused canine thyroid. Selective stimulatory effect of calcium ions.

It is well accepted that the C cells of the thyroid contain somatostatin, but the role in local endocrine function has not yet been firmly established in this organ, and it has not been proved that thyroidal somatostatin is released into the circulation. We have measured the contents of somatostatin-like immunoreactivity in the effluent of canine thyroid glands perfused without recirculation wi...

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ژورنال

عنوان ژورنال: FEBS Letters

سال: 1978

ISSN: 0014-5793

DOI: 10.1016/0014-5793(78)80968-5